CD28

T-CELL SUBSET

Clone & Isotype	Conjugate	Size	Format	Line		Part Number
4B10	FITC	0.5 mL	Liquid	COULTER		6607004
IgG1 (mouse)	RD1	0.5 mL	Liquid	COULTER		6607005
CD28.2	Purified	0.2 mg	Freeze-dried			IM1376
IgG1 (mouse)	Purified	100 tests	Liquid	IOTest		IM1235
	FITC	100 tests	Liquid	IOTest		IM1236
	PE	100 tests	Liquid	IOTest		IM2071

The CD28 antigen (Tp44) is a homodimer of disulfide-linked chains, with a molecular weight of 44 kDa each. It is expressed by a majority of CD3+ T cells. CD4+ T cells express the CD28 antigen more frequently than do CD8+ T cells. CD28 antigen is also present on plasma cells and thymocytes. This antigen is involved in the adhesion of T cells with B cells, through theB7/BB-1 glycoprotein (CD80) or through the B70/B7-2 glycoprotein (CD86). CD28.2 monoclonal antibody activates T cells.It cross-reacts with Rhesus monkey peripheral blood lymphocytes. CD28.2 antibody was evaluated during the Fifth International Workshop on Human Leukocyte Differentiation Antigens.

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CD ROM Vol 2 was produced by staff at the Purdue University Cytometry Laboratories and distributed free of charge as an educational service to the cytometry community. If you have any comments please direct them to Dr. J. Paul Robinson, Professor & Director, PUCL, Purdue University, West Lafayette, IN 47907. Phone:(317) 494-0757; FAX (317) 494-0517; Web http://www.cyto.purdue.edu EMAIL robinson@flowcyt.cyto.purdue.edu