CD27

lymphoid lineage

Clone & Isotype	Conjugate	Size	Format			Part Number
1A4CD27	Purified	0.2 mg	Freeze-dried			IM2034
IgG1 (mouse)					(in dev’t)

The CD27 antigen is a disulfide-linked 120 kDa transmembrane glycoprotein which belongs to the Tumor Necrosis Factor Receptor (TNFR) gene family. It is found on medullary thymocytes, peripheral T cells, activated B cells and Natural Killer (NK) cells. It is preferentially expressed on the CD45RA+ CD45RO-, naive subset of CD4+ T cells. Its recently identified ligand is identical to CD70. 1A4CD27 antibody was evaluated during the Fifth International Workshop on Human Leukocyte Differentiation Antigens.

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CD ROM Vol 2 was produced by staff at the Purdue University Cytometry Laboratories and distributed free of charge as an educational service to the cytometry community. If you have any comments please direct them to Dr. J. Paul Robinson, Professor & Director, PUCL, Purdue University, West Lafayette, IN 47907. Phone:(317) 494-0757; FAX (317) 494-0517; Web http://www.cyto.purdue.edu EMAIL robinson@flowcyt.cyto.purdue.edu