Map 4-Antibodies

CD18

Integrin b2-chain

Clone & Isotype Conjugate Size Format Line Part Number
7E4 Purified 0.2 mg Freeze-dried IM1567
IgG1 (mouse) FITC 100 tests Liquid IOTest IM1568
PE 100 tests liquid IOTest IM1570

The CD18 antigen is the 95 kDa integrin b2-chain which forms non-covalently-bound heterodimers with the integrin a subunits: CD11a, CD11b and CD11c (aL, aM and aX). It is strongly expressed by all human leukocytes. It is known as the receptor for InterCellular Adhesion Molecules (ICAM): ICAM-1, ICAM-2 and ICAM-3 and functions in cell to cell and cell to extracellular matrix adhesion. 7E4 is a blocking antibody in cell adhesion assays.
Home Contents Previous Next
© Coulter International Corporation, 1996. All rights reserved. Copyrights and Trademarks


Products are available FOR RESEARCH USE ONLY (RUO). Unless indicaed FOR IN VITRO DIAGNOSTIC USE (IVD)
Home Page Table of Contents Sponsors Web Sites
CD ROM Vol 2 was produced by staff at the Purdue University Cytometry Laboratories and distributed free of charge as an educational service to the cytometry community. If you have any comments please direct them to Dr. J. Paul Robinson, Professor & Director, PUCL, Purdue University, West Lafayette, IN 47907. Phone:(317) 494-0757; FAX (317) 494-0517; Web http://www.cyto.purdue.edu EMAIL robinson@flowcyt.cyto.purdue.edu