CD11c

Integrin aX-chain

Clone & Isotype	Conjugate	Size	Format	Line		Part Number
BU15	Purified	0.2 mg	Freeze-dried			IM0712
IgG1 (mouse)	PE	100 tests	Liquid	IOTest		IM1760

The CD11c antigen (LeuCAMc) is the 150 kDa integrin aX-chain non-covalently associated with the 95 kDa CD18 antigen(integrin b2). It is expressed by monocytes, granulocytes, macrophages and NK cells. It is also present on activated T and B lymphocytes. It is a member of the b2 integrin family of adhesion molecules. It has been reported as the C3bi and C3dg Complement Receptor (CR4). An additional ligand of CD11c is fibrinogen. BU15 antibody was evaluated during the Third International Workshop on Human Leukocyte Differentiation Antigens.

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CD ROM Vol 2 was produced by staff at the Purdue University Cytometry Laboratories and distributed free of charge as an educational service to the cytometry community. If you have any comments please direct them to Dr. J. Paul Robinson, Professor & Director, PUCL, Purdue University, West Lafayette, IN 47907. Phone:(317) 494-0757; FAX (317) 494-0517; Web http://www.cyto.purdue.edu EMAIL robinson@flowcyt.cyto.purdue.edu