Re: Anti-murine CD16?

Mike Clark (mrc7@cam.ac.uk)
Tue, 30 Jan 1996 17:54:41 +0000 (GMT)

On Fri 26 Jan, a.collins@unsw.edu.au wrote:
> Does anybody know a source of antibody against mouse CD16? The only
> product I have been able to track down reacts with both CD16 and CD32, and
> so is not suitable for my purposes. Any advice would be much appreciated.

I don't recall such a reagent being available. An analysis of the sequences
of the two genes in mouse show that their extracellular domains are very
similar and the main reason for classification as equivalent to human
Fc gamma RII and Fc gamma RIII is based on gene organisation, cytoplasmic
domains and cellular distribution.

If a reagent does exist I would guess that the best company to contact
would be Medarex in the USA (sorry I don't have their address to hand).

Mike Clark, mrc7@cam.ac.uk http://www.path.cam.ac.uk/~mrc7/

-- 
  o/ \\    //            ||  ,_ o   Dr. M.R. Clark, Division of Immunology
 <\__,\\  //   __o       || /  /\,  Cambridge University, Dept. Pathology
  ">    ||   _`\<,_    //  \\ \> |  Tennis Court Rd., Cambridge CB2 1QP
   `    ||  (_)/ (_)  //    \\ \_   Tel. 01223 333705  Fax. 01223 333875


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