Re: CD4 (daily variations)

Bruce S. Edwards (BRUCE@lucy.tli.org)
Mon, 1 Jul 1996 09:40:34 MDT

Elaine, a quality assessment study we published a number of years ago
(Cytometry 10:433-41,1989) addressed your question. We evaluated
freshly prepared peripheral blood lymphocytes from 15 healthy volunteers
over a 19 month period with respect to expression CD4 and several
other membrane proteins (CD3, CD8 and CD20). The median coefficient
of variation for CD4 % positive within the individual volunteers was
4.5% (range 3.2% to 7.8%). Hope this is helpful.
- Bruce

*****************************************************************
>
> Can anyone tell me how CD4 values vary from day to day? (ie. one human,
> tested everyday for a week, for a month, etc.) Is there a reference somewhere?
>
> ************************************
> Elaine Kunze
> Flow Cytometry......Image Analysis
> 8B Althouse Lab
> (814) 863-2762
>
>

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