Re: HIV viral load and flow cytometry: methods & perspectives?

Ray Hicks (rh208@cus.cam.ac.uk)
Mon, 13 Nov 1995 11:03:42 +0000 (GMT)

Hi Bjarne,
There was a paper on PCR-Driven flow cytometry in Science (november
1993 I think), where the researchers claim that they could detect singly
infected cells. I'm afraid that I'm in the process of moving house (I hope),
and my copy of the paper is in a pile of boxes, so I can't give you too
much detailed information, I hope that this is enough to go on.

Ray

On Sat, 11
Nov 1995, Bjarne Moeller wrote:

> The clinicians at our center has confronted me with a few relatively
> simple questions, which I am not able to answer and therefore has
> forwarded to the List of Flow'ers:
>
> We have been wondering if anybody has used flow cytometry to count the
> number of infected cells in HIV-1 patients. Any communications of
> correlation to molecular biology (ie. semiquantitative HIV-1 RNA-PCR)?
>
> If so, is the infected fraction predictive of clinical outcome of HIV-1
> infected patients?
>
> _________________________________________________________________
>
> Bjarne K. Moeller, MD
> Dept. of Clin. Immunology Voice: +45 8949 5304
> University Hospital of Aarhus Fax: +45 8949 6007
> Skejby Sygehus
> DK-8200 Aarhus, Denmark E-mail: bkm@biobase.dk
>
> _________________________________________________________________
>
>
>


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