Re: Clinical Question

STEVEN DAVID GORE (sdgore@welchlink.welch.jhu.edu)
Wed, 28 Feb 1996 09:16:02 -0500 (EST)

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On Mon, 26 Feb 1996, Maryalice Stetler-Stevenson wrote:

>
> Flow: 75% lymphocytes with 97% T-cells. Approximately 70% of the
> lymphocytes are CD3+ T-cells with abnormally dim CD2, CD5 and CD7
> expression; bright CD8; negative for CD56 and CD16 as well as + for CD38
> and HLADR. They are alpha beta T-cells.
> I think this is highly abnormal and I bet malignant. Any comments?
>

Why not T-CLL? I'd see if TCR-beta showed a clonal rearrangement.

Steve GOre
Johns Hopkins Oncology Center

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CD ROM Vol 2 was produced by staff at the Purdue University Cytometry Laboratories and distributed free of charge as an educational service to the cytometry community. If you have any comments please direct them to Dr. J. Paul Robinson, Professor & Director, PUCL, Purdue University, West Lafayette, IN 47907. Phone:(317) 494-0757; FAX (317) 494-0517; Web http://www.cyto.purdue.edu EMAIL robinson@flowcyt.cyto.purdue.edu