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Robert Zucker - Candidate for Secretary

Goals and Objectives

Our society was initially focused on cell analysis primarily using flow cytometry and image analysis. Recently, newer technologies have been developed that use other types of image and flow techniques to analyze cells and tissues. In addition to traditional technologies, it is important to include newer technologies and the scientists who use them in our society because we will all gain from sharing the knowledge of these technologies and their applications. Education in the principles, use, and standards for data interpretation of technologies for analytical cell measurements should be a major focus of our society. As secretary for ISAC, I would like to insure that our society remains committed to serving a wide base of technologies and the scientists who use these technologies.

ISAC had a strong history with a rapid growth from just a few members in the late 1970s to almost 2000 members around 1998. However, the membership has slipped to around 1300-1400 members at present. The organization itself appears to be struggling to maintain identify with the membership and has not been able to bring in new members at a rate to maintain a reasonable growth. Times are changing and I believe that the organization is not as responsive as it should be to the changing face of science and technology around us. I believe that it is a crucial time for the International Society for Analytical Cytology and I would like the opportunity of leading the organization with J. Paul Robinson toward new objectives. I believe that ISAC needs to respond to these changes and revitalize itself. I support Paul Robinson’s aims as president-elect to change the direction of ISAC and revitalize the society.

I feel very privileged to be nominated for the position of Secretary of ISAC. I am personally devoted to both the science that depends on cytometry and the technology itself. I believe that the opportunities for further impact of cytometry are great. The next generation of cell sorters and analyzers produced by all the manufacturers are excellent instruments. They are truly great tools that all people can use. The most exciting technology opportunities may well is in the integration of cytometry and imaging into cell biology to study the functional analysis of cells. This will yield significant capabilities of the ISAC traditional technologies to other scientific disciplines. ISAC now has the capacity to open up exciting new areas for us to integrate our ISAC strengths with other scientific disciplines.

ISAC can play an important part in this new integration. The Society must recognize the changing environment and shift its position to support and manage this changing environment. There are several key things that ISAC needs to do better:

  1. It should better recognize the vitality and importance of students and young members. This is more than providing a few travel fellowships. It must make the next generation of scientists the most important resource the Society has. If I am voted in as Secretary, my tenure will focus on building student, postdoc and junior faculty level membership with active participation in the Society activities. We cannot survive as a society with 10-20 student members. We should have 100-150 student members.
  2. We have an outstanding number of high quality core facility managers and very talented technicians in our society. We have significant technical issues that we deal with on a daily basis and I think these issues should be treated at a much higher value level by ISAC. This aspect of Society activity should be elevated because there is a tremendous level of knowledge in this group and the society can also contribute to the support of these members. Core managers are a key component of our organization and they are one of the best assets we have. ISAC needs to create a platform from which core managers can be supported philosophically and practically so that they can better interact with their respective institutions.
  3. I will raise the level of importance of education and training to the forefront of Society activities. Education should be seen as one of the most important functions of the Society. I believe that we have a great opportunity that is not presently realized.
  4. I will require fiscal responsibility in the ISAC organization and re-focus the organization from a management-focused organization to a membership-focused Society. We spend more money on less people that we have ever spent. The cost of current meetings is unreasonable . We will have to be more careful with YOUR money. We should be proactive and participatory.
  5. I will maintain a constant and open interaction with the membership. You will have direct access to me as a regular member. My email is Zucker.Robert@epa.gov and I will always respond to your concerns. Solicit new members with knowledge and interests that will enrich ISAC.
  6. I will strive to bring the ISAC organization into a position where it interacts with, and impacts other societies and current science policy issues. I value diversity and cultural differences and strongly believe that international cooperation is necessary for ISAC to survive.
  7. I will report to the membership on a frequent basis, and I will seek the opinions and ideas of members.

If you vote for me for Secretary, please also vote for J. Paul Robinson for President-elect. Together we have carefully considered how we can serve ISAC as an executive team. We have thought through the issues and we think we have good ideas. Paul Robinson and I both support the above platform.

ISAC has a rich history of technology development that has resulted in very real impact in many scientific fields. It is my belief that many of the results of technology are yet to come. The next few years promise great opportunities for development of single cell analysis as well as the integration of imaging technologies. Combining these technologies with new proteomics opportunities opens up the field of cytomics. ISAC has an opportunity to take a proactive position to bring academia and industry into new partnerships. To do this, the leadership of the organization must have a philosophical desire to change and approach the future with a plan. I would be privileged to have your support to implement these plans for ISAC during the next few years.

Bob Zucker

Robert M. Zucker received undergraduate (BS in Physics; 1965) and graduate (MS in Biophysics and Nuclear Medicine, 1966; PhD in Biophysics, 1970) degrees from the University of California at Los Angeles (UCLA). His postdoctoral training was in cellular immunology at the Max Plank Institute in Munich, Germany (1970-1972). From 1972 to 1985, Bob directed a research program at the Papanicolaou Institute at the University of Miami (Florida) where he was a faculty member in the Department of Medicine and member of the Sickle Cell Anemia Program. During Bob’s tenure at the Papanicolaou Institute, he studied the effects of chemotherapeutic agents on cancer cells, fetal hemoglobin in sickle cell anemia, cell cycle control mechanisms and the biophysical characterization of cells. In 1985 (to present), Bob became the director of the Core Laboratories for flow cytometry, image analysis, and confocal microscopy for the United States Environmental Protection Agency (USEPA) in Research Triangle Park, North Carolina. His research at the USEPA involves the analysis of toxicological effects of chemicals on tissue culture cells, developing embryos, and reproductive tissues (ovaries/testis) using both flow cytometry and confocal microscopy. Bob is an active member of the international analytical cytology community. At the local level, Bob organized and is an active member of the Research Triangle Cytometry Users Group. Bob was also a member of the Advisory Board of Bioscope at Purdue University, which provides advice for Internet based high school science education.

Bob is a dedicated scientist who has become a leader in his field by applying flow cytometry quality assurance principles to confocal microscopy to acquire more accurate analytical measurements. Bob has received numerous scientific awards at the USEPA for his research and has published over 90 scientific peer-reviewed publications and book chapters during his scientific career. Bob has presented eight workshops on confocal microscopy and/or flow cytometry at national and international scientific meetings. He believes that these advanced educational courses are some of the most important activities we can participate in.

He has served on core study sections at NSF and actively participates as a reviewer for several journals. He has served on ISAC council (elected in 2002) and has been a member of ISAC since its inception. He is active in the Cytometry field with both flow cytometry and confocal microscopy application.

 

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