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Alex Nakeff - Candidate for Clinical Councilor

Statement of Goals and Objectives

It is important that several key initiatives be undertaken to ensure ISAC’s future; these include:

  1. building our junior membership through their more active participation in our governance and at ISAC Congresses (e.g. having the winner of the President’s Award for Excellence sit on Council as a representative of the younger membership),
  2. better recognizing cytometry facility core directors (in which I have spent most of my career) as a vital group of our membership and make more resources available to them,
  3. building stronger alliances with our corporate sponsors, of whom many have been long-time ISAC members, through implementation of successful models, such as that used, on an albeit smaller scale, in GLIIFCA,
  4. building more bridges to the international clinical cytometry community, including more combined meetings,
  5. reaching out to other societies (e.g. AACR, EBMT, ASH, ISEH, ISCT) that utilize flow and image cytometry by making plenary session presentations at their annual meetings to attract their interested membership to join ISAC, in addition to considering some combined meetings to explore merger possibilities,
  6. focusing Council’s efforts on making ISAC more membership-friendly,
  7. improving our financial position through implementation of positive models (1st and 3rd Samuel A. Latt meetings and GLIIFCA) and, lastly, bringing back that “old ISAC spirit” by making our Council activities more transparent.

I am pleased to see that most of my views clearly resonate with those of J. Paul Robinson and Robert Zucker as described on their web-page.

From my perspective gained by serving on ISAC committees, I have come to appreciate the fragile nature, yet great strength, of the international base of ISAC and will commit to work enthusiastically and tirelessly to expand and strengthen our unique ties. I am honored to have been nominated for the position of Clinical Councilor and will be pleased to serve you.

Alex Nakeff

Alexander Nakeff is Professor of Internal Medicine and Director of the Flow Cytometry Core Facility, Henry Ford Health System (HFHS) in Detroit, Michigan, USA. He received his B.Sc. in Science and M.Sc. in Physiology at the University of Toronto and Ph.D. in Radiation Biology and Biophysics (1970) at the University of Rochester, NY. His post-doctoral studies were performed under Dr. van Bekkum at the Radiobiological Institute, TNO, The Netherlands. He joined the Section of Cancer Biology, Washington University, St. Louis, in 1972 as Director of the Core Flow Cytometry Facility, attaining the rank of Associate Professor in 1982. He then joined the Division of Hematology and Oncology at Wayne State University in Detroit, Michigan as Professor of Internal Medicine and Director of the Flow and Image Cytometry Core Facility of the Comprehensive Cancer Center of Detroit (now the Karmanos Comprehensive Cancer Center) in 1986. In 1999, he joined the Drug Discovery and Development Program at the Josephine Ford Cancer Center, HFHS.

His main research interests have been in the regulation of hematopoietic stem cell proliferation and differentiation, with emphasis on megakaryocyte and platelet production and publication of the first paper applying flow cytometry to megakaryocytes in 1979. He has published over 70 peer-reviewed full publications and book chapters, including 3 publications and a review in Cytometry. His present research interests are in cytomics (flow cytometry and proteomics) to determine the molecular mechanism of action of new solid tumor-selective drugs at the proteome level.

He has served on several NIH Special Review committees for flow cytometry, co-founded the Great Lakes International Image and Flow Cytometry Association (GLIIFCA) in 1991 (the best regional group of its kind in the US that is presently in its 13th consecutive year and focused on maximizing the participation of its young members), played key roles in organizing several ISAC Congresses (XIX & XX), served as Chair of both the ISAC Site Selection and Membership Services Committees (the latter formalized the present ISAC Student Awards), initiated and organized the “Under ‘40’s Club” at the last four ISAC Congresses to help attract new, younger members to ISAC and organized and chaired the 3rd Samuel A. Latt meeting in Detroit in 2001 on “Genomics/Proteomics in Cancer” that helped fuel the present ISAC Cytomics initiative.
 

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