Notice that changes in the cytoskeleton (actin shown here in an epithelial cell) result in different adhesion properties. A cancer cell may stop binding neighboring cells and may begin to migrate through the body.

	"Normal"	"Invasive"
Type of adhesion:	Cell-Cell	Cell-Basement Membrane (the surface below the cell)
Will the cell migrate?	Not very well	Yes! (think of the interactions with the surface below as feet that propel the cell to move throughout the body)