RE: DNA PLOIDY AND S-PHASE

DNA PLOIDY AND S-PHASESara

Several recent papers show S-phase as a significant and independent
prognostic indicator in Breast Cancer. These studies were
multi-institutional, utilizing multiple instruments, and examined over one
thousand cases with clinical follow-up data.

DNA AND CELL CYCLE ANALYSIS AS PROGNOSTIC INDICATORS IN BREAST TUMORS
REVISITED, by C. Bruce Bagwell MD, PhD, Gary M. Clark, PhD, Frederique
Spyrantos, DrSc; et al: in New Applications of Flow Cytometry, pp 875-895,
vol 21 Number 4, December 2001, Published by Clinics in Laboratory Medicine

Optimizing Flow Cytometric DNA Ploidy and S-Phase Fraction as Independent
Prognostic Markers for Node-Negative Breast Cancer Specimens; by C. Bruce
Bagwell MD, PhD, Gary M. Clark, PhD, Frederique Spyrantos, DrSc; et al: in
Cytometry (Communications in Clinical Cytometry) 46:121-135 (2001) Published
by Wiley-Liss, Inc.

Adjusting to the new role of DNA Analysis in Breast Cancer Prognosis, Yuan
CM*, Clevenger C, McCarthy T, et.al.: Poster Presented at the Clinical
Cytometry Society's 16th Annual Clinical Applications of Cytometry
Symposium, Coronado Springs Resort, Orlando, FL. November 11-13, 2001
*yuanc@uphs.upenn.edu, University of Pennsylvania School of Medicine, 297
John Morgan Bldg., Philadelphia, PA

Best regards,

Don

Donald J. Herbert
Technical Support Manager
Verity Software House, Inc.
PO Box 247
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Phone: (207) 729-6767 ext.190
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  -----Original Message-----
  From: Markestad, Sara [mailto:SMarkestad@sjha.org]
  Sent: Monday, March 21, 2005 2:26 PM
  To: Cytometry Mailing List
  Subject: DNA PLOIDY AND S-PHASE


  Hello Flowers,

  I am looking for some good recent references for DNA Ploidy and S-phase
for the following tissues:\

	  Breast

	  Colon

	  Kidney

	  Bladder

	  Ovary

	  Prostate

	  Misc. Tissue

	  Endometrium

  We are currently doing some in-house research to see if we should still
continue to provide this testing or if there is another test that will
provide more accurate and better results. Any help would be greatly
appreciated.

  Thank You,

  Sara Markestad, MT (ASCP)

  St. Joseph's Hospital of Atlanta

  404-851-7744



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