RE: Myeloid markers

I am relatively new to flow, but I have read that up-regulation of CD56
and down-regulation of CD11b on maturing myeloid elements, while
non-specific, have been associated with myelodysplasia.
 
Hope this helps.
 
Amy
 
-----Original Message-----
From: Saminathan, Thamarai [mailto:Thamarai.Saminathan@princetonhcs.org]

Sent: Tuesday, January 18, 2005 3:51 PM
To: cyto-inbox
Subject: Myeloid markers
 
Hello clinical flow people,
Anybody looking at myeloid markers and commenting about changes in the
intensity or aberrant expression to support the diagnosis of
myelodysplasia?   If so, how do you report them in the flow reports? We
have an Oncologist who would like to have a base line flow on all his
patients who have bone marrows! I would like to collect data on the
expression of myeloid markers. 
Thank you all,
Thamarai Saminathan
Pathologist
University Medical Center at Princeton
Princeton, NJ
 
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