Emanuel, Plasmacytoid dendritic cells, AKA DC2, express high levels of CD4 and have the phenotype you are noting. However, there are not many of them.... DC2 cells will be screaming positive for CD123 (IL-3R beta chain). Calman > ---------- > From: Emanuel Raniolo > Reply To: emanuel.raniolo@imvs.sa.gov.au > Sent: Tuesday, October 12, 2004 3:11 > To: Cytometry Mailing List > Subject: CD3-CD4+ > > Hi All > > Could someone help me with the identity of a cell population? > Occasionally I have noted a CD3-CD4+CD14- population residing in an area > of > the gating histogram normally confined to NK cells and basophils by > CD45/logSS gating. That is to say that these cells have intermediate > levels > of CD45 expression and side scatter, sitting below and between lymphocyte > and monocyte regions. > The CD4 expression is slightly brighter than monocytes. > Our current case displays 20% of cells with the above phenotype within the > gating region. > Does a normal cell population of that phenotype exist? > > Thankyou, any replies would be appreciated. > > Emanuel Raniolo > Institute of Medical & Veterinary Science > The Queen Elizabeth Hospital Division > Woodville, South Australia > > > > >Received on Thu Oct 14 14:38:00 2004
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