From: A.J. Rossini (rossini@blindglobe.net)
Date: Fri Oct 24 2003 - 17:18:27 EST
"Michael Reitsma" <Michael.Reitsma@stemcellsinc.com> writes: > Esteemed Colleagues, > > I am in need of a software application that fits curves (and > integrates area under the curve) to multi-modal Gaussian > distributions. The data I need to analyze is univariate histograms of > fluorescent reporter gene expression, where we have multiple > subpopulations that overlap to varing degrees. I have tried > (unsuccessfully) to use DNA content analyses software, but it seems to > make too many assumptions based on DNA ploidy, debris, etc. > > Any suggestions? If you mean mixtures of normals (which is what I assume you mean by "multi-modal Gaussian"), and don't mind a bit of programming, I'd look at using R. http://www.r-project.org/ (and the mclust and/or normix packages) best, -tony -- rossini@u.washington.edu http://www.analytics.washington.edu/ Biomedical and Health Informatics University of Washington Biostatistics, SCHARP/HVTN Fred Hutchinson Cancer Research Center UW (Tu/Th/F): 206-616-7630 FAX=206-543-3461 | Voicemail is unreliable FHCRC (M/W): 206-667-7025 FAX=206-667-4812 | use Email CONFIDENTIALITY NOTICE: This e-mail message and any attachments may be confidential and privileged. If you received this message in error, please destroy it and notify the sender. Thank you.
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