From: A.J. Rossini (rossini@blindglobe.net)
Date: Tue Apr 15 2003 - 16:59:22 EST
Boros András dr. <a.boros@richter.hu> writes: > Can you help me to comprehend the K-S analysis offered by CellQuest > software from BD. It says that even the same sample histogram can be > higly significantly different ! What made I wrong ? (Of course I'm > not a mathemathician !) This is a common problem with comparing large datasets. With most "modern" flow data, you reach the point where comparison of distributions resulting from 10k or more per sample will be significant, no matter what you do. It is quite likely that "difference of distributions" is not exactly what you want. Unfortunately, I don't yet have any general suggestions (specific cases, some, but necessarily for all cases). best, -tony -- A.J. Rossini rossini@u.washington.edu http://software.biostat.washington.edu/ Biostatistics, U Washington and Fred Hutchinson Cancer Research Center FHCRC:Tu: 206-667-7025 (fax=4812)|Voicemail is pretty sketchy/use Email UW : Th: 206-543-1044 (fax=3286)|Change last 4 digits of phone to FAX CONFIDENTIALITY NOTICE: This e-mail message and any attachments may be confidential and privileged. If you received this message in error, please destroy it and notify the sender. Thank you.
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