From: Donald E. Mosier (dmosier@scripps.edu)
Date: Wed Nov 25 1998 - 13:33:37 EST
Moesin is an integral membrane protein that shares homology with ezrin and radixin. This family of molecules (ERM) is thought to link cell surface receptors to the cytoskeleton, and each has a cytoplasmic tail that binds to actin. Similar molecules exist in Drosophila, so this is an old and conserved function. We are interested in moesin because its expression is dramatically increased shortly after infection of human T lymphocytes with HIV (Scheuring et al., AIDS 12:563,1998). Don Mosier >Hi, Donald: > >Just by curiosity, what is moesin ? >I am sure that a lot of the others from the List will like to know if they >don't already. > >Thank you > >Michel Canton, PharmD >Managing Director >BioCytex >France > > >>Does anyone know of a source of labeled antibody to human moesin. An >>unlabeled antibody is available from a new company in Lexington KY USA, but >>no labeled Ab is available from that source. >> >> >>______________________________________________________________________________ >>Donald E. Mosier, Ph.D., M.D. >>Department of Immunology IMM7 >>The Scripps Research Institute >>10550 N. Torrey Pines Road >>La Jolla, CA 92037 >> >>619 784-9121 voice >>619 784-9190 fax >> >> >> ______________________________________________________________________________ Donald E. Mosier, Ph.D., M.D. Department of Immunology IMM7 The Scripps Research Institute 10550 N. Torrey Pines Road La Jolla, CA 92037 619 784-9121 voice 619 784-9190 fax
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