From: Anna Porwit-MacDonald (Anja.Porwit@mb.ks.se)
Date: Wed Jun 24 1998 - 09:25:44 EST
Hi, Many T-cell lymphomas lack membrane CD3. In these cases I usually perform also a CD4/Cyt.CD3 staining to check if CD4+ cells are really T cells. Best wishes Anna At 15.16 1998-06-22 -0400, you wrote: > >I just had a cervical node from a 88 yr old male with h/o lymphoma in 1982. >As of yet I have been unable to determine what the phenotype was. In this >biopsy the cells are medium sized; the B cells are polyclonal and >unremarkable. The T cells have all pan T cell markers at about 75% -- except >for CD3 which is expressed on only 24% of the cells. The CD3+ cells are a >mix of CD 4 and CD8, but the CD3- T cells are only CD4. > >Any comments would be welcomed. >Brent Dorsett >Cancer Research Group >Lenox Hill Hospital - NYC > > > Anna Porwit-MacDonald Heamatopathology Lab. Department of Pathology Karolinska Hospital, Stockholm anpo@mb.ks.se tel.:+46-851775863 fax.:+46-851775843
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