From: Michel Canton (mcanton@wcube.fr)
Date: Wed Apr 15 1998 - 02:01:16 EST
Michael, I guess that you are referring to the recent information about IMMUNICON and the anouncement of their collaboration with Dr Arthur Weiss, associate professor of medicine at Allegheny University School of Medicine, who is heading trials of the test. I don't know neither Immunicon or Dr A. Weiss. However I am somewhat familiar with this kind of technique. I do not believe it is flow cytometry. I think it is certainly some kind of cell imaging technology. My guess is that the reagents might be more innovative than the machine itself. At Biocytex, we have been working for several years with the detection of circulating endothelial cells in blood. To achieve that we use magnetic microbeads coated with CD146 MAbs. Then we count the rosettes with a microscope. I understand that Immunicon has developed an automate to ease the fastidious reading. I also understand that their focus is breast and prostate cancer detection. Being very curious, I have located this company: Immunicon Corp. 1310 Masons Mill Huntingdon Valley, PA 19006-3525 Phone: 215- 938 0100 Fax: 215-938 0437 E-mail: immunicon@immunicon.com Web Site: www.immunicon.COM Contact: Dr Paul A. Liberti, CEO I hope that it helps you. Sincerely Michel M. Canton, PharmD Managing Director BIOCYTEX >The front page of our newspaper today describes a new technique for >detecting tumor cells in the blood using magnets to concentrate the >cells. The cited reference is the just released issue of PNAS. Dr >Stewart of Roswell Park is quoted as to the importance of the study. >Although the words "flow cytometry" are not mentioned, I wondered if, in >fact, the concentrated cells are then detected by flow. Is anyone >familiar with this study? How easily adaptable is it for clinical use? >/Michael Kornstein, MD, Richmond, VA > > >
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