From: Ress, S, Stan, Dr (sress@uctgsh1.uct.ac.za)
Date: Thu Apr 02 1998 - 13:29:19 EST
Hi Howard, Teresa Whiteside has published data on the issue of NK variation between donors. There are donors who have reproducibly low or high NKA, these references will help you: 1. Whiteside TL, Bryant J, Day R, Herberman RB. 1990. Natural killer cytotoxicity in the diagnosis of immune dysfunction: criteria for a reproducible assay. J. Clin. Lab. Anal. 4(2):102-114. 2. Whiteside TL. 1991. Natural killer activity in the diagnosis of Immune Dysfunction. Clin. Immunol. Newslett. 11(2):27-31. If you have further questions, let me know as I have someone in the laboratory who has just completed an MSc on serial NK measurements in NHL, and I can pass them on to her. Good luck. Stan. > Date: Wed, 1 Apr 1998 13:33:54 -0500 (EST) > From: Howard Ratech <ratech@aecom.yu.edu> > To: Cytometry Mailing List <cytometry@flowcyt.cyto.purdue.edu> > Subject: Re: Natural Killer Cells > > Dear clinical flow cytometrists: > > I was asked by a reproductive fertility expert how stable are natural > killer cells on repeated determination in healthy people. Apparently, > there is some possibility that high levels of NK cells in females may > predict infertility. Are there any classic studies on absolute NK levels > in normals? > > Thank you in advance for any studies or personal experience. > > Sincerely, > > Howard Ratech, MD Stanley Ress Head: Clinical Immunology laboratory Department of Medicine H47 Old Main Building-room 26 Groote Schuur Hospital and UCT Observatory 7925 Cape Town South Africa TEL:INTERN. + 2721-4066201 or 4066197 FAX: " + 2721-4486815 e-mail: SRESS@uctgsh1.uct.ac.za
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