CD3-CD16/56+CD4+Lymphoma

From: arubin@csnet.net
Date: Tue Sep 04 1990 - 09:56:24 EST

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NK cell lymphomas are a mixed bag.  Many are T cell based. CD8 
positivity is common.  Some CD56+ malignancies are actually acute 
nonlymphoid leukemias.  CD4 positivity would be very strange.  Are 
you sure that the CD4 pattern is not dim staining?  We see this 
commonly in AML.  We have recently seen a young man with a very 
aggressive lymphoma/leukemia showing only CD56 and HLADR positivity. 
There were no T or B cell or myeloid antigens. Malignancy can do 
wierd things(eg "lineage infidelity"). 

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