CD3-CD16/56+CD4+ lymphoma

From: kcdol@samsung.co.kr
Date: Mon Dec 15 1997 - 11:27:57 EST

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Dear flowers

Have you ever seen a CD3-, CD16/56+, CD4+, CD8- lymphoma?
The patient was diagnosed as NK cell lympoma two years ago
and now the lymphoma cells infiltrate bone marrow as well as
peripheral blood.

Flowcytometric analysis shows lymphoma cells do not express
CD2, CD5, CD7, CD3 (surface and cytoplasmic), CD19, CD20, CD10,
FMC7, CD23, CD25, kappa and lambda.

CD16/56 positivity implies NK cell lymphoma but my concern is
CD4 positivity without CD8.

Is this usual pattern of NK cell lymphoma?

Chang-Seok Ki, MD

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