HLA Class I MAbs

From: A.C. JOHNSON (mrpacj@south-01.novell.leeds.ac.uk)
Date: Fri Sep 20 1996 - 12:21:39 EST


Andrew Johnson ~ Clinical Scientist ~ National Blood Service.

I'm involved in a study of class I HLA molecules and I am trying to 
find monoclonal antibodies that bind to different epitopes on the 
molecule, so that it will be possible to completely cover the 
molecule.

Commercially very few clones are available and of these, most 
recognise the same site as W6/32.  A number of monoclonal workshops 
have been involved in this area and as a result a large number of 
monoclonals have been identified.

 Has anybody been involved in these workshops, or do they know of a
 potential source of Class I HLA specific monomorphic MABs ?


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