anti-CD4 antibodies

From: Alice L. Givan (Alice.L.Givan@Dartmouth.EDU)
Date: Thu Nov 17 1994 - 19:16:58 EST

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I have been told that there are two types of anti-CD4 mAbs:  those that bind
to an epitope proximal to the T-cell surface and those that bind to a more
distal epitope.  As I am looking for an antibody that will bind to a site
that is resistant to enzyme digestion,  I would like to try both classes of
mAb.  Does anyone on the flow network have any information about these two
types of anti-CD4 Abs -- and how I can find out which commercial antibodies
fall into which category?  Thanks.
Alice Givan
NCCC Cell Analysis Laboratory
Dartmouth Medical School
Lebanon, NH, USA

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