Gut epithelial cell prep

From: Khattri, Roli (SEA) (Roli.Khattri@sea.celltechgroup.com)
Date: Wed Nov 27 2002 - 13:44:06 EST


Hello colleagues,

Does anyone know of markers that one can use for purifying epithelial cells
and lymphocytes from murine gut using sorters or magnetic beads?  Presumably
for lymphocytes one can use antibodies to the usual markers (CD8, anti-gamma
delta etc).  What about epithelial cells?  Most of the methods I have used
involve collagenase treatment and percoll gradients which can have both
yield and purity issues. I was wondering if there are better methods for
purifying cells from guts?

Thanks.
Roli


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