Re: FITC-labelling of bacteria

From: Hazel Davey (hlr@aber.ac.uk)
Date: Thu Jun 13 2002 - 11:01:18 EST


On 12 Jun 2002 at 9:15, Josef Azem wrote:
>
> Dear Flowers!
>
> Has anyone have a protocoll for FITC-labelling of bacteria?

Straight FITC rather than FITC labelled antibody?

Here is the method I use:

Stock solution of FITC is 1 mg/ml FITC in acetone. Final
concentration of FITC incubated with bacteria should be in the 1-10
ug range depending on sample / cytometer. Incubation for 15 mins is
usually sufficient. I think I adapted this from Miller, J.S. and
Quarles, J.M., 1990. Flow cytometric identification of microorganisms
by dual staining with FITC and PI. Cytometry 11, 667-675.

As usual you may have to adjust this for your circumstances but this
should provide a useful stsrting point.

Hazel--
Hazel Davey HLR@aber.ac.uk http://pcfcij.dbs.aber.ac.uk/
Sefydliad y Gwyddorau Biolegol, Prifysgol Cymru, Aberystwyth
Inst. Biological Sciences, University of Wales, Aberystwyth
http://www.nspcc.org.uk/donate-4-free/donate-mainhome.asp



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