CD4 in granulocytes

From: Arumugham Raghunathan (ragoor@molecularstaging.com)
Date: Mon May 06 2002 - 12:57:39 EST


Dear readers,
I have a pretty simple question (I think!). What is the expression levels of
CD4 in granulocytes (human)? During one of my experiments I noticed that
0.2% of grans are CD4+ve.

In one reference I read it as <1%. My question here is: Do one <1% of the
grans express CD4 (<1 in 100 cells) or is it quantitative in comparison to
T-cells (i.e <1% of the CD4 expression in T cells). Does anyone know of any
relevant references?

Also curious to know what is the significance of the expression of CD4 in
grans.

Thanks a bundle for any helpful response.

Ragoo
***********************************************************
Arumugham Raghunathan, Ph.D
Group Leader, Flow Cytometry Group
Cellular Analysis Section
Molecular Staging Inc.,
300 George Street, Suite 701
New Haven, CT 06510

Tel#    203-772-5074
Fax#   203-776-5278
http://www.molecularstaging.com
*************************************************************



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