Terminology debate

From: Dr Mark W Lowdell (mark@lowood.u-net.com)
Date: Wed Dec 19 2001 - 14:22:38 EST


I agree entirely with Paul on this one.  However, I think the "flow
community" could do more with respect to educating the editors of other
journals.  How often do we still see "mean fluorescence intensity" data
published in high scoring mainstream journals - the same journals also
accept "FL1", "FL2" etc in legends?  In many cases, manuscripts which
rely almost exclusively on flow data to support the hypothesis, present
results which any one of my first year postgrads could see was largely
artefactual - often due to poor compensation,erroneous use of isotype
controls or insufficient sample size.  Is there any mileage in the ISAC
board writing an open letter to editors-in chief of bio-medical journals
suggesting a list of expert flow referees specifically for manuscripts
which rely heavily upon flow data for their conclusions?  There must be
hundreds of "good" flowers out there who regularly teach on flow
courses, write book chapters and submit flow-related manuscripts who
would be prepared to be named on such a list.

Dr Mark W Lowdell
Senior Lecturer in Haematology /
Head of Laboratory of Cellular Therapeutics
RFUCMS

T - 020 7830 2183
F - 020 7794 0645



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