Dear All:
I really need help with this clinical case. A 47 year-old female presented with bilateral cervical lymphadenopathy and hepatomegaly. Her CBC showed 8.5 gm/dl Hb, WBC = 37,900 ( 72% neutrophils, 4% bands, 13% lymphs, Plt = 38,000. BM aspirate report: Numerous blasts ? myeloblasts. Cytochemistry: Sudan black (-), NSE (-), Chloroacetate esterase (-), PAS (-)
Flow cytometry of BM: Blasts are positive for CD7, CD34, CD38, CD (16+56) AND negative for CD4, CD5, CD8, CD10, CD19, CD20, CD23, CD33, CD56, TdT, Myeloperoxidase, Kappa, Lambda, and cytoplasmic CD3 and CD22.
Thank you so much if you can help
Surapon Worapongpaiboon, M.D.
Department of Pathology
Ramathibodi Hospital
Mahidol University
Bangkok, Thailand
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