Hi Could you look for chomosome damage by flow cytometry. I don't know how rare chromosome damage would be. Its not very hard to prepare chomsome preps from rats, either con A stimulated blood or perhaps you could look at granukoma pouch assay cells. Just a thought. We made some chromosome paints for rat and tried to look for abnormal chomosomes by microscopy also. Simon FLOWers I am in need of some help. We want to look at the protective effect of drug X on radiation induced damage in the rat, by Flow Cytometry. Does anyone have any thoughts?? I know this is potentially a very broad subject, but I would appreciate any thoughts on potential avenues of approach thank you for your time and help Philip Barren
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