clinical case

From: Silvana Bonfigli (S.Bonfigli@ipsoe.ss.cnr.it)
Date: Mon Sep 10 2001 - 07:22:44 EST 

I would like to submit a clinical case:
54-year-old male with lymphocytosis ( WBC 50.000 mm3) , splenomegaly
without lymphoadenopathy . Small lymphocytes in the PB, some of them with
nucleoli, small amount of cytoplasm without villous , ipogammaglobulinemia
with a small monoclonal component ( IgG K). At the Immunophenotype the
lymphocytes are: CD19 ++, CD20 ++, CD22 ++, CD23 +, CD10 neg, CD5 neg,
CD11c +, CD103 neg, FMC7 ++.
Which lymphoproliferative disorder could match with this immunopheotype and
such morphology?
Thank you in advance for your help
Silvana

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