PCR on fixed/permeabilized/sorted cells

From: Karim Vermaelen (Karim.Vermaelen@rug.ac.be)
Date: Thu Jun 14 2001 - 10:42:07 EST


Hello again,
I found only little expertise on that subject in the Cytometry archives,
so I thought I'd raise the issue once more... Is it technically feasible
to perform a decent RNA extraction on cells that have been fixed,
permeabilized, labeled for an intracellular marker and FACSorted on that
marker for several hours? Who thinks it's catastrophic, who doesn't?
Thanks a lot for any comments/experience
Karim




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