Dear group, After the recent exchange on the topic of means and ratios in log vs. linear space, I decided to read up on the topic and found some background on all the terms. In particular, thanks to Drs. Shapiro and Roederer for their emails. My question: when fluorescent signal on two groups of patients yields the same frequency (% events relative to isotype control) but different level of fluorescence (log scale) how does one go about showing that they're different? I can put the GM's in excel and get a good P value but with publication in mind I wanted to get some advice from the pro's on the proper ways to do this. This is a study where some cell markers were measured on fixed days over about 2 years. Is it enough to say "we ran FACSComp beads and our normal control data for these markers do not change from lot to lot or month to month so our GM differences in the patient groups are really really true?" I would appreciate any feedback. Maciej ===== `---------------------------------------------` | Maciej S. Simm | 525 E 68th Street | | Research Technician | Room N-805 | | Cornell Medical Center | Tel. 212.746.3428 | `---------------------------------------------` |www.cd4cd8.com | 917-734-6280 | AIM - XsimmX | `---------------------------------------------` __________________________________________________ Do You Yahoo!? Get personalized email addresses from Yahoo! Mail - only $35 a year! http://personal.mail.yahoo.com/
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