Detecting Bacteria

From: Jeff Barry (JBarry@picr.man.ac.uk)
Date: Thu May 24 2001 - 05:11:23 EST


Dear all,

I've recently analysed and sorted a  population of bacteria that were
stained with a fluorescent antibody. Using the fluorescent cells I set the
FSC to log amplification and used SSC (linear) as the thresholding
parameter. This produced great results. However I was a little dubious of
using the ssc (which was weak and ill-defined) as the threshold as it was
difficult to distinguish were "noise" finished and the cell population
actually began.

Any tips or suggestions?

Many thanks,

Jeff Barry
Flow Cytometry
Paterson Institute
Manchester
UK



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