Re: Cell Lines Pre and Post Sort

From: Chris Worth (caw@bcc.louisville.edu)
Date: Tue Apr 10 2001 - 14:54:05 EST


Marty,

Interesting question.


I have always instructed people that bring me cells to do so on a consistent basis with
respect to when they harvest the cells.  Same number of days in culture, same number
of splits post sort, I strive to have every variable  approach a constant.  To simply
make things easier to troubleshoot.  Typically, they are working with confluent growth at
the time we sort them.  If for no other reason than to simply have enough cells.  I can't
provide any insight as to whether waiting for confluency enhances or harms the survival
post sort.

I will look forward to more on this topic.

chris
MoFlo Pilot



On Sun, 1 Apr 2001 11:47:18 -0700, Marty Bigos wrote:

>
>Hi-
>
>A grad student here asked me the following question. I couldn't come
>up with any hard evidence from my experience so I would like to ask
>for any feedback that others may have.  Thanks.
>
>Marty Bigos
>Gladstone Flow Core
>
>"I was wondering what you knew about the affect of sorting a cell
>line on the health of the cells.  Is it thought that you get
>healthier cells out post-sort if the cells start from a confluent or
>not yet confluent plate?  Does it matter?"
>



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