Hi Liza, CD19+CD34+ cells with lymphoid scatter are normal B-cell precursors always present in the bone marrow There are many references available, but I will give you one from the European CA on MRD where frequencies in normal bone marrow and differences in patterns between children and adults are described: Lucio P, et al. B-cell Differentiation. I. Flow Cytometric Analysis of Normal Bone Marrow : a Frame for Reference for the Detection of Minimal Residual Disease in Precursor B-ALL. Leukemia 1999; 13: 419-427 Kind regards Anna At 15:16 2001-01-31 -0500, you wrote: > Hi there flowers, Does anyone have any theories, thoughts and/or >explanations for a CD34+CD19+ population on human cells? I've come across >this more than once and I am a bit confused as to what it means exactly. >Thank you for your assistance. Liza McGuire >Thomas Jefferson University Hospital >130 S 9th Street, Rm. 400 Edison >Philadelphia, PA 19107-5233 >(215)955-9646 Anna Porwit Hematopathology Lab. Department of Pathology, Radiumhemmet Karolinska Hospital, 171 76 Stockholm, Sweden Anja.Porwit@ks.se tel.:+46-851774518 fax.:+46-851775843
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