Re: very rare events: how low can you go?

From: Maciej Simm (simmmmer@yahoo.com)
Date: Mon Jan 29 2001 - 21:01:09 EST


This was talked about on this group as well. I remember that the main
idea was to increase the overall events to make the small population
statistics more significant.. there was a link to a website which
discusses the math behind that but I lost it. Hope this helps,

maciej

--- Lynn Dustin <dustinl@mail.rockefeller.edu> wrote:
>
> Hello all,
>
> This question arises from a rather heated discussion following a
> seminar
> yesterday, in which the speaker claimed that flow cytometry is not
> useful for analyzing cells that are less than 1-2% of the starting
> population. I am sure that with all of the sorting, multicolor
> analysis,
> and multiparameter gating that people do, we can prove this
> assertion
> wrong.
>
> If you have experience or publications with analysis of events well
> below 1% of the starting cell population, could you please share
> some
> examples or references?
>
> Thanks in advance for your help!
> **********************************************
> Lynn B. Dustin, Ph.D.
> Center for the Study of Hepatitis C
> Rockefeller University
> Box 64
> 1230  York Ave.
> New York, New York 10021
> Phone: 212-327-7067
> email: dustinl@mail.rockefeller.edu
>



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