Re: unstable FACScan readings

From: Mark A. KuKuruga (kukuru@umich.edu)
Date: Thu Oct 05 2000 - 14:31:55 EST


Snezna,
These analyzers work as closed systems, from sheath to waste.  As a
result, sometimes the waste side of the fluidics can be clogged or
restricted.  This may result in a slowing of flow through the flow cell,
thus increasing the time each event spends in the laser beam.  The
result is a remarkable increase in all signals (do you see this effect
on light scatter as well?).  Check to be sure that there is no
restriction to the waste tank.
Other than that, I'm sure there are also electronic problems that can
cause this effect . . . go to BD for help there.
MAK.

Snezna Rogelj wrote:

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--
Mark A. KuKuruga, Managing Director
University of Michigan Core Flow Cytometry
<http://www.cancer.med.umich.edu/flow_cytometry>
phone: 734-647-3216  fax: 734-936-7376
kukuru@umich.edu



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