Dear Francesca, I agree with Anna, it might be. CD38 should be positive as well and cytoplasmic light chain. Morphology of IC might sometimes resemble to PLL in terms of necleoli. CLL is unlikely. But... These type questions remind me to the following: The animal is grey and has four legs. Dear expert what do you think? The weight would strengthen my idead it might be an elephant. So... whats about morphology and complete blood count and lymph nodes and spleen size and electrophoresis? NHL diagnosis cannot be based solely on flow. You become an expert if you ask these questions yourself. Doing NHL in flow without microscopy doesn´t make any sense. The new digital cameras for 500 USD make nice pictures connected to the microscope which might be stored directly to jpeg, small enough to share them by e-mail. Its just the price of one reagent bottle of monoclonals. And dont stop asking questions ;-). Thomas Dr. med. C. Thomas Nebe Facharzt für Laboratoriumsmedizin Universitaetsklinikum Mannheim Zentrallabor Theodor-Kutzer-Ufer 1-3 D-68167 Mannheim Tel. +49 621 383-3485 FAX +49 621 383-73 3485 (PC) +49 621 383-3819 (paper) e-mail: thomas.nebe@ikc.ma.uni-heidelberg.de http://www.ma.uni-heidelberg.de/inst/ikc/ (Internet) http://pandora/inst/ikc/ (Intranet)
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