Dear Flowers, although this is not an exactly flow-related question: does anybody know of a commercial or non-commercial source of a blocking antibody against human CTLA-4 (CD152), as well as an activating antibody against human CD40 ? Both antibodies are intended to be used in cocultures of T cells and antigen-pulsed APCs in vitro. With regard to anti-CTLA-4: I would like to use the antibody to selectively block CTLA-4/ B7 interactions between T cells and APCs, while leaving CD28/ B7 interactions intact (in contrast to the fusion protein CTLA-4-Ig which blocks both). Thanks in advance for any help. Alex Alexander Kiani, MD Medizinische Klinik und Poliklinik I Technische Universität Dresden Fetscherstr. 74 D - 01307 Dresden Germany Tel. +49-351-458-5617, -3610, -3311 Fax +49-351-458-5370 E-mail: kiani@oncocenter.de
This archive was generated by hypermail 2b29 : Sat Mar 10 2001 - 19:31:32 EST