What do you mean morphology consistent with PLL/CLL, and histo suggests marginal zone lymphoma? Histo of what? If the spleen is removed and is consistent with marginal zone- I would be happy with that diagnosis. How broght was the CD11c- like hairy cell or dim? What about CD20- was it normal, dim or bright? Sounds like a good case. Maryalice >Hi Flowers! > >We have a patient who is an 82 yo F. 90% of lymphoid cells in the >peripheral blood are CD19+CD20+FMC7+CD11c+. >CD22 and CD25 are weakly positive (just), and they are >Kappa-Lambda-CD23-CD5-CD103-CD9-. >70% of cells in the bone marrow have the same profile. >Morphology is consistent with PLL/CLL, and histo suggests marginal zone >lymphoma. >Spleen is not enlarged. > >Any suggestions? > > >Beth Rees > >Flow Cytometry Laboratory >Royal Hobart Hospital >Hobart >Tasmania, Australia Maryalice Stetler-Stevenson Director Flow Cytometry Unit Laboratory of Pathology, NCI, NIH
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