Re: problems with time delay calibration on FACS Calibur

From: Larry Arnold (lwarma@med.unc.edu)
Date: Tue Jun 27 2000 - 15:25:16 EST


Warren

We have had a 2 laser Calibur for about 1 year.  Have never seen the
problem except occasionally when someone doesn't get the sheath supply tank
cap not sealed tight.  Could you have a pressure leak there or somewhere
else?  The time delay is very sensitive to sheath pressure because of
course it affects the speed of transit of the cells which needs to be
precise since the lasers are set to a fixed distance apart.

Larry

At 05:07 PM 6/26/2000 -0400, you wrote:

>Dear Flowers (in particular FACS Calibur users),
>
>We have a new FACS Calibur and have had persistent problems with
>reproducibly being able to set time delay calibration.  In
>particular, we get the error message, "signal out of range...unable
>to set time delay."  BD has replaced an EPROM and a board, but the
>problem intermittently persists.  In speaking to users of 3 other
>Caliburs I discovered that they too had seen this problem.  I'd
>appreciate any comments from other two laser users on the Calibur and
>will summarize the responses to the list.  Many thanks.
>
>
>Warren
>
>
>Warren D. Shlomchik, M.D.
>Assistant Professor of Medicine
>Yale University School of Medicine
>Section of Medical Oncology
>333 Cedar Street  WWW217
>New Haven, CT  06520
>
>phone:(203)737-2478
>FAX: (520)395-8571

Larry W. Arnold, Ph.D.
Res. Assoc. Prof.
Director, Flow Cytometry Facility
Department of Microbiology and Immunology
Lineberger Comprehensive CAncer Center
CB# 7290
University of North Carolina at Chapel Hill
Chapel Hill, NC 27599
Phone: 919-966-1530
FAX: 919-962-8103



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