TruCount vs Flow Count beads -Reply

From: Mike Keeney (Mike.Keeney@lhsc.on.ca)
Date: Fri May 19 2000 - 08:49:11 EST


Hi Susan,

You don't need to compensate for the beads in any channel. Both FlowCOUNT and TruCOUNT
are broad spectrum beads which can be detected in any FL channel  as a discrete bright
peak. We usually look for them in FL3. If you are doing single color FITC staining
use either FL2 or FL3 for the bead and adjust the PMT to put them in the top third of
your histogram. If you look at beads versus time you can easily monitor the fluidics
of the system or if there are any problems during aquisition.

Michael Keeney ART,FIMLS
Technical Specialist
Hematology/Flow Cytometry
London Health Sciences Centre
800 Commissioners Road East
London, Ontario
Canada
N6A 4G5
519 685 8300 ext 52187
fax 519 685 8360

>>> "Susan Dawes-SM" <dawes.sm@pg.com> 05/18 2:30 pm >>>

Hello All,

I am in need of beads to use for absolute counts of cells which are stained with
a very bright fluorescein analog.  Does anyone have experience with either
TruCounts or Flow Count beads with FITC-stained cells?  Have you had problems
with compensation between The Fitc and Pe channels?  Any comments would be
appreciated. Thanks

Susan Dawes
Procter & Gamble
Miami Valley Labs
dawes.sm@pg.com



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