True count substitute

From: Arnold Pizzey (a.pizzey@ucl.ac.uk)
Date: Thu May 11 2000 - 03:30:51 EST


At 09:21 09/05/00 -0400, you wrote:
>
>
>
>Dear Flowers,
>
>BD does not make the TruCount tubes available without buying it with their
kits
>(that we do not need). Does anyone know a similar product for cell
counting on a
>flow cytometer?
>
>Thanks,
>
>Akos Szilvasi
>Biogen, Cambridge, MA
>
>
>
>
>
Greetings Akos,

I have been using the following method to obtain absolute counts by flow;

1) centrifuge 5ml of Beckman-Coulter Flow-check Fluorospheres 400g 10mins.

2) Discard supernatent and resuspend in 5ml fetal bovine serum

3) centrifuge as above and resuspend in 5ml fetal bovine serum

4) Count beads by haemocytometer (the hard part - I count around 1000 beads)

5) Add beads to sample and analyse by flow.


regards,

Arnold

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	Arnold Richard Pizzey
	Department of Haematology
	Royal Free and University College London Medical School
	98 Chenies Mews
	London WC1E 6HX
	U.K

	voice:	+44 020-7679-6234
	Fax:	+44 020-7679-6222
	email:	a.pizzey@ucl.ac.uk
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