Re: PMT for Cy7?

From: FACS_COPY@wehi.edu.au
Date: Tue Apr 04 2000 - 00:41:24 EST


Marty,

> The 636-10 is GaAs type PMT. Although they have better spectral
> responses in the red than the 3896, 928, 1477 types, their gain is an
> order of magnitude less. Thus, the match may not be optimal for the
> preamp system gains that BD uses. Have you (or anyone else reading
> this) had any experience with these PMTs?

In 1996, we specified a type R636-10 for our MoFlo before the specs on
the R3896 were available to us.  It was supplied as Cytomation type
H957-11. Hamamatsu's specs (http://www.hpk.co.jp/HP2E/main.html) show
cathode radiant sensitivities at 800nm of about 15, 40 and 60 mA/W for
types R928, R3896 and R636-10 respectively.  I'm persuaded that the
less than 30% cathode sensitivity improvement of the R636-10 over the
R3896 is not worth the lower gain (about 20-fold).  On the other hand,
200V more PMT volts should give a decade more gain.  In fact we
typically run our R636-10 PMT at 750V which is 100-200V more than the
FITC and PE detectors.

You can see an actual result at
http://www.wehi.edu.au/cytometry/FCMexamples.html#apccy7 but we
haven't done the comparison with any other PMT.

Frank.

Frank Battye,        \    /       < The Cytometry Laboratory
Dora Kaminaris,       \__/   <<<<<  The Walter & Eliza Hall Institute
Viki Lapatis,    ------!!<<<<<<<<   Victoria  3050,   AUSTRALIA
Jennie Parker and     /!!\   <<<<<  ph: 61_3_9345 2540 fax: 61_3_9347 0852
Catherine Tarlinton  o !! \       < in::   "facs_copy@wehi.edu.au"



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