HOW viable after high-speed sorting?

From: Cliff McArthur (cytocliff@netscape.net)
Date: Mon Mar 06 2000 - 12:16:45 EST


Hi there, flow aficionados.

I know we've all addressed the post-sort viability (after high-speed sorting)
question many times over.  What I am looking for is not "whether" but "how
much," so to speak.  To that end, I'd like to ask the List if anyone knows of
any published work that has addressed the question not of whether or not cells
are viable after such sorting (we know they are, or can be) but "how" viable,
that is, do they produce less cytokine or other product, proliferate a little
more slowly, or survive for less time, etc., etc. under the same conditions
versus "low-speed" sorted cells?  Shucks, references that just address this
question, if it is not the primary objective of the work, would be great to
have.

If anyone is willing to share their unpublished insights, I'd love to hear
them as well.

Thank you very much,
Cliff McArthur
University of California at San Francisco
Departments of Medicine and Immunology/Microbiology
415-502-6860

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