Aurora Biosciences Corporation is a leader in the application of novel fluorescence technologies for functional analysis in mammalian cells and high throughput screening for drug discovery. We currently have an excellent opportunity for a flow cytometry operator available in our facility supporting a dynamic range of research through the use of novel proprietary fluorescent dyes and assays. Under the supervision of Aurora's flow cytometry core facility staff, the incumbent will perform cell sorting using two multi-laser FACSVantage SE Turbo sorters, analytical flow cytometry using a BD LSR multi laser benchtop flow cytometer, and other related fluorescence applications using state of the art fluorescence plate readers, fluorescence microscopes and imaging systems. The successful applicant will perform daily sterile sorting of pools and single cell clones, maintain quality control of cell sorters, analyze/interpret data and recommend sorting strategies to researchers. Most sorting will be based on functional responses such as gene expression, calcium flux, and membrane potential in addition to conventional flow cytometric applications such as cell cycle, apoptosis and immunophenotyping. Experience with Aurora fluorescence technologies is not necessary, but a firm command of instrument optimization and troubleshooting is required. Other duties will include daily maintenance and upkeep of the flow cytometry core facility and experiment optimization. Requires a BS degree (with a background in cellular or molecular biology preferred) and 2-5 years experience in flow cytometry (with some sorting experience) or equivalent experience. A strong understanding of flow cytometry theory and principle is important. Must have excellent organizational, communication and interpersonal skills, ability to optimize experimental procedures, interpret data and modify methods and protocols. Experience with Becton Dickinson flow cytometers and Macintosh computers a plus. For questions pertaining to this position contact Eric Hare at (858) 404-8409 or e-mail address: haree@aurorabio.com Aurora offers a competitive salary, benefits, and equity participation including an ISO and Stock Purchase Program. For more information on Aurora, please refer to <http:/www.aurorabio.com>. For consideration, please send your resume and cover letter to: Human Resources, Aurora Biosciences Corporation, 11010 Torreyana Rd., San Diego, CA 92121, Fax: (858) 404-6720 or E-mail: SylvesterK@aurorabio.com EOE.
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