Dear All, We have just had a new leukaemic with the following immunophenotype: Positive for CD19, CD22, CD20, CD10, cCD79a, CD34, HLADR, CD38, CD45, TdT AND cCD3 (the latter is weak positive in comparison to the residual normal cCD3+ cells) Negative for all other markers including surface CD3, CD7, CD2, CD5 and CD1a. All myeloid markers are negative. Is this a true biphenotypic leukaemia or a mistake? Thanks for your help. Sarah Lawson (isaac.lawson@btinternet.com)
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