RE: FACS question

From: Gerstein, Rachel (Rachel.Gerstein@umassmed.edu)
Date: Tue Dec 11 2001 - 17:17:35 EST


Hi

we use rhodamine 123 to measure P-gp activity in conjunction with detecting
PE in FL2 and Cy5-PE in FL3.  It requires significant compensation but it
works.  Let me know if you need further info.

Best wishes,
Rachel

=======================================================
Rachel M. Gerstein, Ph.D.
Department of Molecular Genetics and Microbiology
Graduate Program in Immunology/Virology
University of Massachusetts Medical School
55 Lake Avenue North
Worcester, MA 01655-0002
(508) 856-1044
(508) 856-5920 (FAX)


> ----------
> From:		Laura Hodges
> Sent:		Monday, December 10, 2001 2:58 PM
> To:	Cytometry Mailing List
> Subject:	FACS question
>
>
> I'd like to post a question on your website:
>
>
> Can anyone suggest another P-gp accumulation probe
> other than rhodamine 123 which has too broad of an
> emission spectrum for my use.  I am trying to find a
> P-gp probe that can be used with other fluorescent
> markers in channels FL2, FL3, and FL4 in a multicolor
> assay.
>
>
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