Placental tissue

From: Kayoko Kimura (kkimura@nadc.ars.usda.gov)
Date: Fri Sep 21 2001 - 13:44:03 EST


Dear Flowers,

I have been trying to isolate cells from bovine placenta (cotyledon specifically) and
examine cell surface markers using flow cytometry.  I have several (many ?) problems.
One problem is keeping samples.  I cannot get placental samples easily, then I would
like to keep placental tissue for later use if possible.  Now I use only "fresh (taken
just after expulsion or peeled from uterus after calving)" or one day old samples
kept at 4 C.  Does anyone know how to keep placental tissue for a long time so that I
can isolate cells later and stain cell surface markers and intracellular cytokines?
If tissue storage is impossible, how about isolated cells?  Can I keep these cells
for a long time for later staining?

Kayoko Kimura
DVM, Ph.D
Periparturient Disease of Cattle Research Unit
National Animal Disease Center
USDA-ARS
Box 70, 2300 Dayton Rd.
Ames, IA  50010
515-663-7374



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